(Previously offered as 567.2)
Drs. Quilley and Nasjletti
This is a detailed analysis of the pharmacologic effects of naturally occurring autocrine and paracrine hormones (autacoids) including histamine, serotonin, angiotensin, kinins, substance P, growth factors, cytokines, prostaglandins, and leukotrienes. Questions to be addressed include the role of autacoids in basic physiology and their value as drugs or targets of drug action in various disease states.
Prerequisites: PHRM-1010 or 1020 is a pre- or co-requisite.
Lectures: 2 hrs/wk. Letter-graded.