The growth of complementary and alternative medicine (CAM) is widespread in the United States. While many healthcare professionals support their use, there are others who remain quite skeptical about efficacy and usefulness. The course teaches the fundamentals of the most important and widely applied forms of alternative therapies, and approaches the subject in a scientific way while preserving the founding theories of different disciplines. Issues surrounding efficacy, effectiveness, and safety are discussed. Government regulations and reimbursement concerning various CAM therapies are summarized.