Intramural 

   Cardiology (Dr. P. Anversa; Medicine) "Telomere length as a measure of proliferation in myoblasts"  

   Oncology (Drs. E. Feldman and K. Seiter; Medicine/Oncology) "Study of apoptosis in bone marrow and peripheral blood of leukemia patients during treatment"; "Determination of the role of apoptosis and expression of cyclin D3, p16, bcl-2 and bax in the progression of myelodysplastic syndrome in the presence and absence of treatment with human chorionic gonadotropin" 

   Pathology (Drs. M. Melamed and W. Gorczyca; Pathology) "Study of apoptosis in solid tumors"; "Study of cyclin expression in solid tumors"  

   Biochemistry (Dr. Joseph Wu; Biochemistry and Molecular Biology) "Studies of the antitumor properties of the dietary supplement PC SPES"; "Identification of the agent responsible for granulocytic ehrlichiosis in peripheral blood samples"; "Cell cycle effects and control of gene expression be resveratrol in human breast tumor cells with different metastatic potential"

   Childrens Cancer Research Fund (S. Mayer, Drs. C. Sandoval and S. Jayabose; Pediatric Oncology/Hematology) "Incidence and clinical relevance of lymphoid-associated genotypic markers in pediatric AML" 

   Neurosurgery (Dr. W. Couldwell) "Analysis of the sensitivity of glioblastoma cells to different antitumor drugs"

Extramural 

   Thomas Jefferson University (Dr. B. Calabretta) "Leukemia treatment in SCID mice by antisense oligonucleotides targeting cooperating oncogenes"  

   Sloan-Kettering Institute (Dr. C. Cordon-Cardo) "Use of new probes of cyclins and cyclin dependent kinase inhibitors to study the interaction of these complexes and the relationship in cancer versus normal cells"  

   American Health Foundation (Dr. Anthony Albino) "Study of cyclin and cyclin-dependent kinase inhibitor expression in melanocytes and melanoma cell lines grown in the presence and absence of differentiating agents"; "Growth characteristics of p16 null melanoma cell lines following transfection with wild-type p16"

Commercial 

   Eli Lilly & Co. Characterization of the growth characteristics of cells transfected with a cell cycle control gene and their response to various proprietary agents.  

   Pharmingen The role of underphosphorylated pRb in tumors and as a tool for screening antitumor drugs. Testing the use of NFk B as a marker of cell sensitivity to antitumor agents, particularly TNF. 

   AlfaCell Study of Onconase^TM - Determination of the mechanism of action of Onconase^TM; Characterization of possible synergy between Onconase^TM and other chemotherapeutic agents. 

   Milkhaus Laboratories Study of human chorionic gonadotropin (hCG) - Study of the ability of hCG to induce apoptosis and downregulate bcl-2 in patients with acute leukemia. To determine whether treatment with hCG predisposes tumor cells to undergo apoptosis when treated with conventional chemotherapeutic agents. Study of the efficacy of hCG in the treatment of MDS (myelodysplastic syndrome): correlation of clinical outcome with apoptosis, expression of Cyclin D3, p16, bcl-2, bax and ras as well as the ratios Cyc D3/p16 and bcl-2/bax. 

   Botanic Labs Study of the mechanism of action of the natural herbal mixture PC SPES^TM and its ability to inhibit growth of prostate cancer cells. Study of the active ingredients in the individual components of PC-SPES and the contribution to the overall activity of the mixture.