CELL 1320 Lectures in Histology

(Previously offered as 132A.3)

This course involves the study of individual cells and the organization in tissues and organ systems. Emphasis is on the correlation of structure and function at all levels of organization. Lectures: 3hrs/wk. Letter-graded. Students cannot apply credit for both CELL 1320 and CELL 1420 to their degree requirements.

CELL 1330 Laboratory in Histology

(Previously offered as 132B.2)

Laboratory sessions involving microscopic analysis of slides consisting of human and animal tissues and organs. Laboratory: 4 hrs/wk. Co-requisite: CELL 1330. Letter-graded. Enrollment is limited. Microscopes are required with a limited number available for rental.

CELL 1360 Cell Biology

(Previously offered as 136.3)

This course is concerned primarily with eukaryotic cells. Lectures are devoted to structural details and the molecular functions of the different parts of the cell. Lectures will introduce topics such as endocytosis, intramembrane transport, protein targeting, organelle biosynthesis, protein sorting, exocytosis, cell shape, motility, and cell-to-cell interaction. Lectures also deal with signal transduction processes and cellular functions that are required for cell growth and programmed cell death. By its completion, students should have a comprehensive understanding of the architecture and function of living cells. In addition, emphasis is placed on experimental approaches taken to elucidate certain biology principles, including “paper review sessions” with active participation by students. Prerequisite: General Biochemistry I (BIOC 1010) or equivalent. Lectures: 3 hrs/wk. Letter-graded.

CELL 1410 Gross and Developmental Anatomy

(Previously offered as 141.9)

This course is designed to provide the student with a working knowledge of the gross anatomical structures of the human body, their functional relationships and their development. Emphasis is placed on the regional dissection of the entire cadaver. Laboratory sessions begin with a discussion of the structures to be dissected. Lectures introduce regions or systems, supplemented with TV tapes of prosections and demonstrations. Lectures by faculty from the Department of Surgery emphasize the relevance of anatomical principles to clinical application. Conferences conducted by members of the Radiology Department reinforce anatomical principles with radiographs, computerized tomography and magnetic resonance images. Small group sessions and a problem-solving approach to the material is favored throughout the course. Human development is presented by a combination of lectures and conferences outlining the embryogenesis of specific organ systems, small-group problem-solving sessions and lectures emphasizing the clinical application of embryology to neonatology and pediatrics. Open to Ph.D. students only. Laboratory 90 hrs. Lectures-Conferences: 75 hrs. Letter-graded.

CELL 1420 Histology Cell Biology

(Previously offered as 142.6)

This course presents the structural organization and correlated function of the microanatomy of the human body. Since the cell is the basic element of all tissues, particular attention is paid to aspects of molecular and cell biology. New methods for studying structure and function are discussed. Lectures incorporate aspects of gross anatomy, embryology, histophysiology and histopathology to establish a foundation of integrated knowledge. In the laboratory, students study structural aspects by viewing prepared microscope slides and related electron micrographs. Several lectures are devoted to the clinical aspects of special topics in Cell Biology and Histology. Open to Ph.D. students only. Lectures: 52 hrs, Laboratory-Conference: 70 hrs. Letter-graded. Students cannot apply credit for both CELL 1420 and CELL 1320, 1330 to their degree requirements.

CELL 2110 Developmental Neurobiology

(Previously offered as 175.3)

This course is intended to present up-to-date information on various aspects of the developing nervous system. Specific lectures will review the historical aspects followed by the recent status of each problem. The 3rd hour will be devoted to the discussion of one or two specific papers in the subject. Lectures: 3 hrs/wk. Letter-graded.

CELL 2120 Developmental Biology

(Previously offered as 184.2)

Topics in molecular and cell biology of developing and regenerating systems. Subjects include fertilization, cell differentiation, chromatin structure and function, molecular control of gene expression, cellular pattern formation, neuronal specificity, the extracellular matrix, and the cellular basis of morphogenetic movements. Lectures: 2 hrs/wk. Letter-graded.

CELL 3110 Cytokines

(Previously offered as 185.2)

This course covers the structure and function of cytokines such as the interleukins, interferons, and cellular growth factors. Emphasis will be on a consideration of cytokines involved in the host reaction to infection and injury, in B and T cell proliferation and in hematopoictic cell differentiation. Lectures: 2 hrs/wk. Letter-graded. Prerequisites: CELL 1360 and BIOC 1250.

CELL 8010 Journal Club

(Previously offered as 191.1)

Students present and critically discuss current papers in a selected area. Seminar: 1hr/wk. Pass/Fail. May be taken multiple times.

CELL 8020 Research Seminar

(Previously offered as 190.1)

The student presents a seminar in his/her own field of interest and attends the weekly seminars presented by invited guests, faculty members and students. Seminar: 1 hr/wk. Pass/Fail. May be taken multiple times.

CELL 8100 Current Topics in Cell Biology and Neuroscience

Dr. Etlinger and Staff (Fall and Spring)

(Previously offered as 194.2)

Areas at the "cutting edge" of modern biology are studied at an advanced level through lectures, students’ presentations and critical discussions. Two to four topics are covered each semester. Topics include but are not limited to the following: Receptor mediated endocytosis, growth factors and ocogenes, ubiquitin and cellular function, interaction of extracellular matrix with normal and transformed cells, regeneration of muscle and nerve, neuronal plasticity in visual systems, neurobiology of learning, molecular basis of cell cycle, molecular basis of signal transduction, programmed cell death. Seminar: 2hrs/wk. Letter-graded.

(Previously offered as 196A Gross Anatomy, 196B Histology-Cell Biology, 196C Neural Science.)

Students assist the faculty in teaching departmental courses to medical students. Hours to be arranged. Pass/Fail. Open to Ph.D. students only.

CELL 9110 Introduction to Research in Cell Biology and Neuroscience  

(Previously offered as 193.2)

Training in experimental design and interpretation of data as well as hands-on experience with various state-of-the-art techniques used in modern research. Individualized interaction is provided in a faculty laboratory for approximately one semester. Within the context of an experimental question, students have the opportunity to learn diverse techniques including tissue culture, electrophysiology, confocal microscopy, recombinant DNA, digital imaging, protein chemistry and FPLC, immunohistochemistry, etc. Students present a “work in progress” seminar at the conclusion of each rotation. Research: Hours to be arranged. Pass/Fail. Open to Ph.D. students only, who must take this course twice.

CELL 9750 Master’s Literature Review

(Previously offered as 197.1)

Candidates for the Master of Science degree in Cell Biology and Anatomy may elect a Library project to satisfy, in part, the degree requirement. A research review topic is chosen after consultation between the student and faculty advisor and this serves the basis of a literature review with submission of a satisfactory final written report. Required for the Master’s degree, Plan A. Independent study. Pass/Fail. Open to Master’s students only.

CELL 9800 Master's Thesis Research

(Previously offered as 198.1-5)

Candidates for the Master of Science degree in Cell Biology and Anatomy may elect to conduct a research project under the supervision of a faculty member. Submission of an acceptable final report summarizing results is required (CELL 9850). Thesis Research. Pass/Fail. May be taken multiple times, for one to five credits per term, but only five credits can be applied towards program requirements. Open to Master’s students only.

CELL 9850 Master’s Thesis

(Previously offered as 195.1)

The candidate writes a scholarly thesis describing his/her original research in cell biology or anatomy (CELL 9800). The thesis must be approved by a graduate faculty committee. Open to Master’s students only. Required for the Master’s Degree, Plan B. Independent study. Pass /Fail.

CELL 9900 Doctoral Dissertation Research

(Previously offered as 199.1-15)

Candidates for the doctoral degree elect this course while performing research under the guidance of a faculty member. Thesis Research. Pass/Fail. May be taken multiple times for an overall total of 15 credits. Open to Ph.D. students only.

BMS 1410 Neural Science

(Previously offered as 922.8)

Fine structure and gross anatomy of the nervous system, including pathways, are emphasized together with the fundamentals of membrane physiology, neuropharmacology and experimental evidence elucidating conduction of nervous impulses. Reflex activity and integration of function by the central nervous system are dealt with on a theoretical basis and from a clinical point of view. Lectures and conferences: 100 hrs., laboratory demonstrations and clinical sessions: 100 hrs. Letter-graded. Open to Ph.D. students only.

BIOC 2630 Cell Signaling

(Previously offered as 263.2)

An advanced topic course that covers major signaling components such as phospholipases, GTP binding proteins, protein kinases, and protein phosphatases. Format includes lectures by the instructors and presentations of original literature by the students. Prerequisite: BIOC-1010 or CELL-1360. Lectures: 2 hrs/wk. Letter-graded. Enrollment is limited.