MICRO 1010 General Microbiology
(Previously offered as 321.4;
previously entitled Fundamentals of Microbiology
prior to Fall 2003)

A course in the biology of microorganisms with an emphasis on bacteria. The course covers microbial structure, function, physiology and growth. The fundamental biological properties will be related to the role of microorganisms in nature and the means by which they are manipulated in the laboratory. Lectures: 4 hrs/wk. Letter-graded. Students cannot earn credit for this course if they have previously earned credit for MICRO 1410.

MICRO 1410 Medical Microbiology
(Previously offered as 341.8)

This course is designed to give the student insight into the fundamentals of microbiology with emphasis on its relation to human biology and disease. The course covers the basic properties of microorganisms, microbial physiology and genetics, the principles of microbial pathogenicity, the mode of action of antibiotic and chemotherapeutic agents at the cellular level, the fundamentals of immunology, and the response of the host to infections. The microorganisms studied in this course include the bacteria, fungi, mycoplasmas, rickettsiae, chlamydiae, viruses and parasites. By integrating lectures, laboratory work, visual aids, case histories, and group discussions, the student will learn the concepts of microbiology and the application of microbiological techniques for research and diagnosis. Lectures: 80 hrs/16 wks. Laboratory: 48 hrs/12 wks. Letter-graded. Open to Ph.D. students only.

MICRO 2010 Basic Immunology
(previously offered as 345.1)

An introductory text-based course designed to enable students to comprehend the basic concepts of immune function and regulation. Lectures: 2 hrs/wk. Letter-graded.

MICRO 2020 Advanced Immunology
(Previously offered as 347.2)

This course covers advanced topics in immunology and deals with both innate and adaptive immune responses. Discussions of special topics are based on published reviews and research articles. The course also examines clinical aberrations of the immune system and a detailed analysis of the involvement of the immune parameters in either augmenting or initiating a disease. Emerging clinical applications of immunological research are also discussed. Lectures and discussion: 2 hrs/wk. Letter-graded. Prerequisites: MICRO 1410 or MICRO 2010.

MICRO 2110 Virology
(Previously offered as 346.3)

A comprehensive course devoted to the field of virology with special emphasis on the architecture and characteristics of viruses, the infectious cycle, and the replication of viral nucleic acids. Examples of representative viruses will be used to discuss the several classes of nucleic acid in the virion. Lectures: 3 hrs/wk. Letter-graded. Prerequisite: a course in biochemistry.

MICRO 2120 Microbial Genetics
(Previously offered as 351.3)

Using E. coli and its bacteriophages as a model system and emphasizing genetic methodology, this course covers the study of recombination, genetic mapping, gene transfer, mutation, regulation of gene transfer, regulation of gene expression of essential genes, transpositions, gene fusions and genetic engineering. Lectures: 3 hrs/wk. Letter-graded. Prerequisite: a course in biochemistry.

MICRO 2140 Microbial Pathogenicity
(Previously offered as 370.24.2 and as MICRO 4130.)

A course covering the molecular aspects of microbial pathogenicity. The pathogenic properties of bacteria and other microorganisms will be discussed. Special emphasis will be given to the molecular and genetic aspects that are relevant to the epidemiology of infectious diseases. Lectures: 2 hrs/wk. Letter-graded. Prerequisite: MICRO 1010 or MICRO 1410.

MICRO 2210 Molecular Biology
(Previously offered as 355.3)

A comprehensive course covering the in vitro and in vivo aspects of DNA, RNA, and protein synthesis in prokaryotic organisms. Lectures: 3 hrs/wk. Letter-graded. Prerequisite: a course in biochemistry.

MICRO 2310 Molecular Biology & Immunology of Tumor Cells
(Previously offered as 370.7.2)

This course will describe antigenic and biochemical properties of tumor cells, development of host immune responses, and use of monoclonal antibodies in identification and characterization of tumor-associated antigens. The application of hybridoma technology, molecular biology, and immunology research to the treatment and diagnosis of human malignant disease processes will be emphasized. Lectures: 2hrs/wk. Letter-graded.

MICRO 3010 Adhesion Molecules
(Previously offered as 370.1.2)

The identification and structural characterization of cellular adhesion molecules will be described. The developmental and immunobiological functions of these molecules in cell-cell and cell-extracellular matrix interactions will be discussed. Lectures: 2 hrs/wk. Letter-graded.

MICRO 3210 Signal Transduction
(Previously offered as 370.4.2)

The molecular mechanisms by which eukaryotic cells transduce external stimuli to intracellular signals will be examined. The components of various signaling pathways will be described and their functional effects on cell regulation will be discussed. Lectures: 2 hrs/wk. Letter-graded.

MICRO 3230 Principles of Biological Therapy
(Previously offered as 370.8.2)

This course covers the theory and principles of biological therapy including gene therapy and immunotherapy as applied to cancer, infectious diseases, autoimmune diseases, and genetic diseases. Lectures: 2hrs/wk. Letter-graded.

MICRO 4110 Advanced Virology
(Previously offered as 370.43.2)

A study of the recent advances in virus-host interactions and viral genetics. Lectures: 2 hrs/wk. Letter-graded. Prerequisite: MICRO 2110.

MICRO 4210 Epidemiology of Infectious Diseases
(Previously offered as 370.41.2)

Several viral, bacterial, and parasitic diseases, their occurrence, control, and the properties of the infectious agents will be discussed with emphasis on epidemiological principles. Lectures: 2 hrs/wk. Letter-graded.

MICRO 8020 Departmental Seminar
(Previously offered as 390.1)

Discussion of selected topics in microbiology and immunology. Students present papers and are expected to participate actively in the discussion. Seminar: 1 hr/wk. Pass/Fail. May be taken for credit multiple times, but only four credits may be counted toward Ph.D. degree requirements. May not be counted towards M.S. degree requirements.

MICRO 9110 Techniques in Microbiology and Immunology
(Previously offered as 380.x.2)

Fundamental laboratory techniques in microbiology to be learned in the research laboratories of the department. This course is intended for first-year Ph.D. students undertaking research rotations. Research: hours to be arranged. Consent of instructor is required. Pass/Fail.

MICRO 9750 Master’s Literature Review
(Previously offered as 397.1)

The student writes a scholarly review of the scientific literature on a selected topic, approved by a faculty advisor. The finished document must be approved by a faculty committee. Required for the Master’s degree, Plan A. Independent study. Pass/Fail.

MICRO 9800 Master’s Thesis Research
(Previously offered as 398.1-5)

Research related to the student's thesis topic performed under the supervision and guidance of a faculty advisor. A student may register for this course more than once, for 1-5 credits per term, but only five total credits may be counted towards M.S., Plan B requirements. Thesis research: hours to be arranged. Pass/Fail.

MICRO 9850 Master’s Thesis
(Previously offered as 395.1)

The student writes a scholarly report describing the background, rationale and results of an original laboratory investigation. (See MICRO 9800). Required for the Master’s degree, Plan B. Independent study. Pass/Fail.

MICRO 9900 Doctoral Dissertation Research
(Previously offered as 399.1-15)

Research related to the student's Ph.D. dissertation topic performed under the supervision and guidance of a faculty advisor. A student may register for this course more than once for an overall total of 15 credits. Thesis research: hours to be arranged. Pass/Fail.