| Currently we are funded by the National Heart Lung and
Blood Institute (NHLBI) of the National Institutes of Health and the
American Heart Association to perform
research grants investigating the role of circulatory
dysfunction and respiratory dysfunction in postural tachycardia syndrome
(POTS). Further NIH funding for studies of specific central nervous system
effects of nitric oxide and angiotensin are pending as does a renewal of CFS
funding.
We have solicited patients for the POTS study since September 2004 and
this is on-going although the precise experiments have changed to
include basic mechanisms of central nervous system control of blood
pressure in subsets of POTS patients. Additionally we have observed
similarities among findings in low flow POTS patients and in patients
with forms of kidney disease with and without renal failure, and in
young subjects with obesity related metabolic syndrome both of which are
the subjects of funded investigations.
NIH Studies:
Local
Vasoconstriction in Postural Tachycardia Syndrome (August
2004 -2009, Patient Enrollment Opens September 1, 2004)
Vascular Dysfunction in Chronic
Fatigue Syndrome (April 2008-April 2012)Patient Enrollment Opens July 1,
2008)
Endothelial Cell Dysfunction in
Chronic Renal Failure
AHA Study:
Hyperpnea in Postural
Tachycardia Syndrome.
New York State Empire Clinical
Research Investigator Program (ECRIP)
Irritable Bowel Syndrome
(IBS) and Autonomic Dysfunction
Children's Hospital Study:
Microvasular Function in
Metabolic Syndrome in Obese Adolescents
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