|Currently we are funded by the National Heart Lung and
Blood Institute (NHLBI) of the National Institutes of Health to perform
research studies investigating the role of circulatory
dysfunction in postural tachycardia syndrome (POTS) and in Postural
Vasovagal Syncope. Further funding has been obtained from the CFIDS
Society to study neurocognitive deficits ("Brain Fog") in
patients with the Chronic Fatigue Syndrome (CFS) and with POTS.
We have solicited patients for this and an earlier POTS study since September 2004.
The study is on-going although the precise experiments have changed to
include basic mechanisms of central nervous system control of blood
pressure in subsets of POTS patients. Moreover neurocognitive deficits
(lightheadedness, brain fogi, memory loss0 have taken center stage and may
be intimately related to altered relationships between cerebral blood flow
and blood pressure.
Vasoconstriction in Postural Tachycardia Syndrome (July 2010 -2015, Patient Enrollment
Opened September 1,
of Vasovagal Syncope (March 2013-2017), Patient Enrollment Open in April
Fog in Chronic Fatigue Syndrome
Vascular Dysfunction in Chronic
Fatigue Syndrome (April 2008-April 2013)Patient Enrollment Opened July 1,
2008). This study is now closed.
Hyperpnea in Postural
Tachycardia Syndrome. This study is closed as an NIH study but is
continuing to recruit several patients per year.