CRISPR Will Never Be Good Enough To Improve People
The CRISPR/Cas9 (CRISPR) technique has been used to modify genes in animals, plants and fungi, organisms different from and more complex than the bacteria in which the molecular components originally evolved. It has undergone several refinements since its introduction, each iteration proving more accurate, with fewer off-target effects. The Stanford University bioethicist Hank Greely contemplates using CRISPR to touch up human embryos that have been produced by in vitro fertilization and prescreened for overall suitability by gene sequencing. George Church, a Harvard University genetic technologist and entrepreneur, advocates a more aggressive program of CRISPR-mediated genetic improvements to future generations.
NYMC Faculty: Stuart A. Newman, Ph.D., professor of cell biology and anatomy