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Use of Radioisotopes in Biology and Medicine PHYS 2920 Summer 2003
Date	Topic	Instructor
June 03	Introduction: Course Administration, Syllabus, Examination, Text. Elements of Nuclear Physics, Atomic Structure, Nomenclature, Natural and Artificial Radioactivity, Half-life, Decay Law, Decay Constant, Specific Activity, Decay Chains	M. Mozzor
June 05	Properties of Alpha, Beta, Gamma, X-rays, and Neutrons. Specific Energy Loss, Stopping Power, Range, Relative Hazard, Bremsstrahlung, Wave properties, Interaction of Radiation with Matter	M. Mozzor
June 10	Radiation Measurement and Dose Determination: Terms, Quality Factor, exposure, Absorbed Dose, Dose Equivalents	M. Mozzor
June 12	Biological Effects: Sensitivity, Early Somatic Effects, Late Somatic Effects, Heredity Effects, Stochastic and Non-Stochastic Effects. Risk Biological response to Specific Organs	M. Mozzor
June 17	Internal and External Dosimetry	D. Quinn
June 19	Radiation Detection Principals	M. Mozzor
June 24	Radiation Detection Instrument, Counting Statistics	M. Mozzor, Dr. C. Thompson
June 26	Radiation Protection Standards, Health Physics Principals Take Home Mid-Term Exams Distributed	M. Mozzor
July 1	No class - Term paper Topic Approval Due
July 3	No class
July 8	Use of radioisotopes to measure ion transport	Dr. N Levine
July 10	Use of Radioisotopes in Phosporylation Reactions	Dr. K. Lerea
July 15	Use of Radioisotopes to identify lipid second messengers	Dr. S. Olson
July 17	Use of Radioisotopes in immunochemistry	Dr. C. Hamby
July 22	DNA Hybridization	Dr. J. Edwards
July 24	Use of Radioisotopes in peptide binding reactions	Dr. C. Thompson
July 29	Use of Radioisotopes to measure cardiac metabolism	Dr. F. Recchia
July 31	Term Papers Due

1. Course Title: Use of Radioisotopes in Biology and Medicine

Catalogue Number: PHYS 2920

2. Course Director: Dr. T. Hintze, Professor, Dept. of Physiology

E-mail Thomas_hintze@nymc.org

3. First Half Instructor: Matty Mozzor, RRPT, Radiation Safety Officer

Phone 914-594-4448

E-Mail matty_ mozzor@nymc.edu

Catalogue Description:

Course Description: The main objective of this course is to provide an introduction to radiation protection for all users of radiation sources in a laboratory environment. The course is divided into two sections. The first section is a general discussion of radiation physics, radiation biology, radiation dosimetry, radiation detection systems, and regulation of radiation use.

The second half of the course provides an overview of specific radioisotope use in research, biology, and medicine.

Number of Credits: This is a two-credit course.

Prerequisites: The students should have some basic knowledge of physics.

Program Requirements: None

Required Text: Radiation Protection: A Guide for Scientists and Physicians, Jacob Shapiro, Harvard Press, 2002, 4^th edition

Evaluation: The students will be evaluated based on in-class participation, homework assignments, mid-term exam and a final paper according to the following criteria:

In-class participation: 5%

Homework assignments 10%

Midterm 40%

Paper 45%

The paper will explore a topic of radiation protection, radioisotope use or radiation effects, as selected by the student. Specific guidance for the paper requirements will be provided during the course.