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1932 - 2003
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Chironian Fall/Winter 2003

HYPERTENSION IS DEADLY FROM ANY VIEWPOINT

TNF-alpha and IL-6 are inflammatory cytokines, proteins initially studied for their significant roles in immuno- logical and inflammatory events. In this issue we report on research by a pharmacologist and a cell biologist that shows how these molecules may be involved in essential and pulmonary hypertension. Though their scientific methods differ, the investigators share the same goal: to determine exactly what causes different kinds of hypertension.

This photograph using DIC Nomarsky microscopy demon- strates Dr. Ferreri's finding that all TAL cells in the kidney are not the same. COX-2 protein is expressed only in a subset of TAL cells (dark brown ), while neighboring TAL cells (blue) do not express the protein. These distinct populations of cells may have different functions regarding the control of salt balance in the body.

- PHOTO COURTESY OF CARLOS VIO, M.D.

Reinhard E. Zachrau, M.D., is professor of pathology, but that's the least of his challenges. He is charged with scheduling every second-year student not only for his course, Pathology/Pathophysiology, but also for every course taken that year. Students consistently rate his "path" course best and vote him one of their best teachers. (Photo - LEFT)

Urologists are among the surgical specialists who use robots in their practice. Alum Gerald Matthews, M.D. '86, has used the da Vinci robot shown here to help restore male fertility. It is mainly used now for suturing inside the body in a variety of surgical situations. (PHOTO COURTESY OF DA VINCI SURGICAL SYSTEM) (Photo - CENTER)

Supervising the Cardiovascular Research Institute's laboratories of Piero Anversa, M.D., are Annarosa Leri, M.D., and Jan Kajstura, Ph.D. They use the multi-focal microscope for experiments in the living heart, where the scientists are looking for movement of stem cells away from the site of storage to the area of injury. (Photo - RIGHT)