NYMC > Departments > Academic Departments > School of Medicine > Urology > Research

Research

Background (1996 - present)

Urology Research Laboratory has been officially established in 1996 with commitment of the late Dr. Camille Mallouh, former Chairman and Emeritus Professor. Sensuke (Konno) Sato, Ph.D., is an Associate Professor and the full-time Research Director, who has been conducting the multifaceted research projects since 1996.  Dr. Konno (Sato) and the urology residents and medical students of New York Medical College have published 72 papers in the prestigious journals, made 130 presentations at the major national and international meetings and conferences, and also won over 25 awards and prizes in those meetings/conferences. 

Research Projects

The followings are the current (on-going) research projects being performed under Dr. Konno’s supervision:           

  • Critical role of oxidative stress in nephrolithiasis and its potential prevention with specific antioxidants
  • Prevention of renal ischemic/reperfusion injury with conventional and alternative approaches and their possible mechanisms
  • Assessment of possible insulin-like activity of SX-fraction (mushroom extract) with hypoglycemic effect: Prophylactic modality of diabetic nephropathy
  • Possible improvement of chemotherapeutic efficacy with “complementary” agents in the prognostic status of urological cancers (including prostate, bladder and renal cell carcinomas)
  • Investigation of the molecular basis of urological malignancies and exploration of the improved therapeutic modalities with alternative or unconventional agents (e.g., vitamin C, 2-deoxy-glucose, beta-glucan, proanthocyanidin etc.) 

 

Research Publications: (1996 – Present)

  1. Nakajima, Y., Konno, S., Perruccio, E., Chen, Y., Wu, J.M., An, S., Chiao, J.W., Choudhury, M., Mallouh, C. and Muraki, J.: Effects of IFN-b on growth of human prostatic JCA-1 cells. Biochem. Biophys. Res. Commun., 200: 467-474, 1994.
  2. Novichenko, N., Konno, S., Nakajima, Y., Hsieh, T.C., Xu, W., Turo, K., Ahmed,  T. and Chiao, J.W.: Growth attenuation in a human prostate cell line mediated by a phorbol ester. Proc. Soc. Exp. Biol. Med., 209: 152-156, 1995.
  3. Konno, S., Hsieh, T.C., Wu, J.M., Chen, Y., Chiao, J.W. and Mallouh, C.: Growth control of human prostatic cancer cells by the phorbol ester TPA: Possible involvement of protein kinases. Anticancer Res., 16: 1843-1850, 1996.
  4. Oya, M., Konno, S., Chen, Y., Tazaki, H., Mallouh, C. and Wu, J.M.: Control of cell cycle regulatory proteins and modulation of STAT1 proteins by IFN-g in human prostatic JCA-1 cells. Int. J. Oncol., 10: 835-839, 1997.
  5. Konno, S., Cherry, J.P., Tazaki, H., Mallouh, C. and Chiao, J.W.: Effects of protein kinase and phosphatase inhibitors on the growth of human prostatic cancer cells. Med. Sci. Res., 25: 353-354, 1997.
  6. Mordente, J.A., Konno, S., Chen, Y., Wu, J.M., Tazaki, H. and Mallouh, C.: The effects of brefeldin A (BFA) on cell cycle progression involving the modulation of the retinoblastoma protein (pRB) in PC-3 prostate cancer cells. J. Urol., 159: 275- 279, 1998.
  7. Mordente, J.A., Cherry, J.P., Chapman, J., Choudhury, M.S., Tazaki, H., Mallouh,C. and Konno, S.: The maturation of cathepsin D as a possible predictor of prostate cancer progression. Mol. Urol., 2: 1-5, 1998.
  8. Konno, S., Mordente, J.A., Chen, Y., Wu, J.M., Tazaki, H. and Mallouh, C.: Effects of brefeldin A on androgen receptor-mediated cellular responses in human prostatic carcinoma LNCaP cells. Mol. Urol., 2: 7-11, 1998.
  9. Mordente, J.A., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S.: Hydrolysis of androgen receptor by cathepsin D: Its biological significance in human prostate cancer. Br. J. Urol., 82: 431-435, 1998.
  10. Cherry, J.P., Mordente, J.A., Chapman, J.R., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S.: Analysis of cathepsin D forms and their clinical implication in human prostate cancer. J. Urol., 160: 2223-2228, 1998.
  11. Davidson, S.D., Cherry, J.P., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S.: Glyoxalase I activity in human prostate cancer: A potential marker and importance in chemotherapy. J. Urol., 161: 690-691, 1999.
  12. Chapman, J.R., Tazaki, H., Mallouh, C. and Konno, S.: Mechanism of brefeldin A- induced growth inhibition and cell death in human prostatic carcinoma cells. Mol. Urol., 3: 11-16, 1999.
  13. Chapman, J.R., Tazaki, H., Mallouh, C. and Konno, S.: Brefeldin A-induced apoptosis in prostatic cancer DU-145 cells: A possible p53-independent death pathway. BJU Int., 83: 703-708, 1999.
  14. Samadi, A.A., Davidson, S.D., Mordente, J.A., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S.: Differential glycosylation of cellular prostate specific antigen and the regulatory mechanism of its secretion. Mol. Urol., 3: 147-152, 1999.
  15. Won, J.H., Parekattil, S.J., Davidson, S.D., Luddy, J.S., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S.: Ammonium chloride-induced prostatic hypertrophy in vitro: Urinary ammonia as a potential risk factor for benign prostatic hyperplasia. Urol. Res., 27: 376-381, 1999.
  16. Milanesa, D.M., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S.: Methylglyoxal-induced apoptosis in human prostate carcinoma: Potential modality for prostate cancer treatment. Eur. Urol., 37: 728-734, 2000.
  17. Nowzari, F.B., Davidson, S.D., Eshghi, M., Mallouh, C., Tazaki, H. and Konno, S.: Adverse cellular effects of oxidative stress on renal cells and its prevention by antioxidants. Mol. Urol., 4: 15-19, 2000.
  18. Fullerton, S.A., Samadi, A.A., Tortorelis, D.G., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S.: Induction of apoptosis in human prostatic cancer cells with b-glucan (Maitake mushroom polysaccharide). Mol. Urol., 4: 7-13, 2000.
  19. Hettiarachchi, J.A., Johnson, G.B., Panageas, E., Drinis, S., Konno, S. and Das, A.K.: Malignant priapism associated with metastatic urethral carcinoma. Urol. Int., 66: 114-116, 2001.
  20. Drinis, S., Finkelstein, M.P., Tortorelis, D.G., Konno, S. and Choudhury, M.S.: Five-year prognosis after radical prostatectomy in a patient with localized prostate cancer and incidental non-Hodgkin’s lymphoma. Urol. Int., 66: 105-107, 2001.
  21. Samadi, A.A., Fullerton, S.A., Tortorelis, D.G., Johnson, G.B., Davidson, S.D., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S.: Glyoxalase I phenotype as a potential risk factor for prostate carcinoma. Urology, 57: 183-187, 2001.
  22. Konno, S.: Maitake D-fraction: Apoptosis inducer and immune enhancer. Altern. Complement. Ther., 7: 102-107, 2001.
  23. Konno, S., Cherry, J.P., Mordente, J.A., Chapman, J.R., Choudhury, M.S., Mallouh, C. and Tazaki, H.: Role of cathepsin D in prostate cancer cell growth and its regulation by brefeldin A. World J. Urol., 19: 234-239, 2001.
  24. Konno, S., Tortorelis, D.G., Fullerton, S.A., Samadi, A.A., Hettiarachchi, J.A. and Tazaki, H.: A possible hypoglycaemic effect of maitake mushroom on type 2 diabetic patients. Diabet. Med., 18: 1010, 2001.
  25. Konno, S.: Maitake SX-fraction: Possible hypoglycemic effect on diabetes mellitus. Altern. Complement. Ther., 7: 366-370, 2001.
  26. Finkelstein, M.P., Drinis, S., Tortorelis, D.G., Lafaro, R.J., Konno, S. and Choudhury, M.S.: Recurrence of renal cell carcinoma with extensive vena caval thrombus three years after radical nephrectomy. Urol. Int., 68: 199-201, 2002.
  27. Davidson, S.D., Milanesa, D.M., Mallouh, C., Choudhury, M.S., Tazaki, H. and Konno, S.: A possible regulatory role of glyoxalase I in cell viability of human prostate cancer. Urol. Res., 30: 116-121, 2002.
  28. Hettiarachchi, J.A., Samadi, A.A., Konno, S. and Das, A.K.: Holmium laser enucleation for large (>100 ml) prostate glands. Int. J. Urol., 9: 233-236, 2002.
  29. Aynehchi, S., Samadi, A.A., Gallo, S.J., Konno, S., Tazaki, H. and Eshghi, M.: Salvage extracorporeal shockwave lithotripsy after failed distal ureteroscopy. J. Endourol., 16: 355-358, 2002.
  30. Konno, S., Aynehchi, S., Dolin, D.J., Schwartz, A.M., Choudhury, M.S. and Tazaki, H.: Anticancer and hypoglycemic effects of polysaccharides in edible and medicinal maitake mushroom [Grifola frondosa (Dicks.: Fr.) S.F. Gray]. Int. J. Med. Mushrooms, 4: 185-195, 2002.
  31. Finkelstein, M.P., Aynehchi, S., Samadi, A.A., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S.: Chemosensitization of carmustine with maitake b-glucan on androgen-independent prostatic cancer cells: Involvement of glyoxalase I. J. Altern. Complement. Med., 8: 573-580, 2002.
  32. Konno, S.: Maitake D-fraction: A potent mushroom extract product against human malignancies. Townsend Lett., 233: 96-100, 2002.
  33. Konno, S.: Maitake D-Fraction: Apoptosis inducer and immune enhancer (II).Explore, 11: 19-23, 2002.
  34. Preuss, H. and Konno, S.: (Book) Maitake Magic. Freedom Press, Topanga, CA, 2002.
  35. Konno, S.: SX-fraction: Great promise for treatment of syndrome X and type II diabetes. Explore, 12: 20-23, 2003.
  36. Konno, S.: Maitake D-fraction: A promising natural agent for alternative cancer treatment. Original Intern., 9: 44-48, 2003.
  37. Hettiarachchi, J.A., Finkelstein, M.P., Schwartz, A.M., Johnson, G.B., Konno, S. and Choudhury, M.S.: Benign retroperitoneal schwannoma presenting as a giant adrenal tumor. Urol. Int., 71: 231-232, 2003.
  38. Konno, S.: Potential health benefits from medicinal mushrooms. Today’s Chiropractic, 32: 52-57, 2003.
  39. Konno, S.: Maitake SX-fraction: Unique mushroom extract for treatment of syndrome X and type II diabetes mellitus. Natural Pharmacy, 7: 16-17, 2003.
  40. Glauco, S., Jano, F., Paolo, G. and Konno, S.: Safety of maitake D-fraction in healthy subjects: Assessment of common hematologic parameters. Altern. Complement. Ther., 10: 228-230, 2004.
  41. Konno, S.: Potential growth inhibitory effect of maitake D-fraction on canine cancer cells. Vet. Ther., 5: 263-271, 2004.
  42. Preuss, H.G., Konno, S. and Bagchi, D.: (Book Chapter) Overview of the use of maitake mushroom and fraction D in cancer. In: Phytopharmaceuticals in cancer chemoprevention. Edited by Bagchi, D. and Preuss, H.G. London: CRC Press; pp. 509-517, 2004.
  43. Konno, S.: Medicinal and cosmetic properties of mushroom and pearl. Explore, 16: 7-9, 2007.
  44. Konno, S.: Effect of various natural products on growth of bladder cancer cells: Two promising mushroom extracts. Altern. Med. Rev., 12: 63-68, 2007.
  45. Pyo, P., Louie, B., Rajamahanty, S., Choudhury, M. and Konno, S.: Possible immunotherapeutic potentiation with D-fraction in prostate cancer cells. J. Hematol. Oncol., 1: 25-33, 2008.
  46. Rajamahanty, S., Louie, B., O’Neill, C., Choudhury, M. and Konno, S.: Possible disease remission in patient with invasive bladder cancer with D-fraction regimen. Int. J. Gen. Med., 2: 15-17, 2009.
  47. Konno, S.: Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy. Int. J. Gen. Med., 2: 91-108, 2009.
  48. Cang, S., Feng, J., Konno, S., Han, L., Liu, K., Sharma, S.C., Choudhury, M. and Chiao, J.W.: Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells. Int. J. Oncol., 35: 1417-1422, 2009.
  49. Louie, B., Rajamahanty, S., Pyo, P., Choudhury, M. and Konno, S.: Mode of cytotoxic action of nephrotoxic agents: oxidative stress and glutathione-dependent enzyme. BJU Int., 105: 264-268, 2010.
  50. Rajamahanty, S., Alonzo, C., Aynehchi, S., Choudhury, M. and Konno, S.: Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor. J. Biomed. Sci., 17: 5-10, 2010.
  51. Louie, B., Rajamahanty, S., Won, J., Choudhury, M. and Konno, S.: Synergistic potentiation of interferon activity with D-fraction on bladder cancer cells. BJU Int., 105: 1011-1015, 2010.
  52. Davalos, M., Konno, S., Eshghi, M. and Choudhury, M.: Oxidative renal cell injury induced by calcium oxalate crystal and renoprotection with antioxidants: a possible role of oxidative stress in nephrolithiasis. J. Endourol., 24: 339-345, 2010.
  53. Fishman, A.I., Johnson, B., Alexander, B., Won, J., Choudhury, M. and Konno, S.: Additively enhanced antiproliferative effect of interferon combined with proanthocyanidin on bladder cancer cells. J. Cancer, 3: 107-112, 2012.
  54. Fishman, A.I., Alexander, B., Eshghi, M., Choudhury, M. and Konno, S.: Nephrotoxin-induced renal cell injury involving biochemical alterations and its prevention with antioxidant. J. Clin. Med. Res., 4: 95-101, 2012.
  55. Konno, S., Alexander, B. and Choudhury, M.: An alternative therapeutic approach to various cancers with combinations of chemotherapeutic drugs or vitamin C and D-fraction. Townsend Lett., Aug./Sep.: 23-26, 2012.
  56. Alexander, B., Fishman, A., Green, D., Choudhury, M. and Konno, S.: Attenuation of androgenic regulation by brefeldin A in androgen-responsive prostate cancer cells. Urol. Oncol., 31: 104-109, 2013.
  57. Alexander, B., Fishman, A.I., Eshghi, M., Choudhury, M., and Konno, S.: Induction of cell death in renal cell carcinoma with combination of D-fraction and vitamin C. Integr. Cancer Ther., 12: 442-448, 2013.
  58. Konno, S., Alexander, B., Zade, J. and Choudhury, M.: Possible hypoglycemic action of SX-fraction targeting insulin signal transduction pathway. Int. J. Gen. Med., 6: 181-187, 2013.
  59. Konno, S., Alexander, B., Freilich, D. and Choudhury, M.: Improved anticancer effects on various cancers with combinations of chemotherapeutic drugs or vitamin C and D-fraction. J. Cancer Ther., 4: 843-850, 2013.
  60. Fishman, A.I., Green, D., Lynch, A., Choudhury, M., Eshghi, M. and Konno, S.: Preventive effect of specific antioxidant on oxidative renal cell injury associated with renal crystal formation. Urology, 82: 489.e1-489.e8, 2013.
  61. Degen, M., Alexander, B., Choudhury, M., Eshghi, M. and Konno, S.: Alternative therapeutic approach to renal-cell carcinoma: Induction of apoptosis with combination of vitamin K3 and D-fraction. J. Endourol., 27: 1499-1503, 2013.
  62. Freilich, D., Moskowitz, E., Feuer, N., Choudhury, M., Phillips, J. and Konno, S.: Possible chemosensitizing and potent anticancer effects of D-fraction in combination with vitamin C on three prevalent urologic cancer cells. J. Cancer Ther., 5: 1402-1411, 2014.
  63. Konno, S.: (Book Chapter) Biological significance and medicinal properties of the maitake mushroom. In: Mushrooms: Cultivation, Antioxidant Properties and Health Benefits. Edited by Pesti, G. Hauppauge: Nova Science Publishers, Inc.; pp. 1-42, 2014.
  64. Konno, S.: Beneficial neurological effects of Amyloban 3399: A product made form bioactive extracts of lion’s mane (Hericium erinaceum). Townsend Lett., Oct.: 81-85, 2014.
  65. Konno, S., Chu, K., Feuer, N., Phillips, J. and Choudhury, M.: Potent anticancer effects of bioactive mushroom extracts (Phellinus linteus) on a variety of human cancer cells. J. Clin. Med. Res., 7: 76-82, 2015.
  66. Bhalodi, A., Ferretti, M., Chaimowitz, M., Choudhury, M., Phillips, J. and Konno, S.: Alternative therapeutic approach to urothelial cell carcinoma with medicinal mushroom extracts. J. Cancer Res. Treat., 4: 73-79, 2016.
  67. Schulman, A., Chaimowitz, M., Choudhury, M., Eshghi, M. and Konno, S.: Antioxidant and renoprotective effects of mushroom extract: Implication in prevention of nephrolithiasis. J. Clin. Med. Res., 8: 908-915, 2016.
  68. Valera, V., Ferretti, M., Prabharasuth, D., Chaimowitz, M., Choudhury, M., Phillips, J. and Konno, S.: Is targeting glycolysis with 2-deoxyglucose a viable therapeutic approach to bladder cancer? Int. J. Cancer Ther. Oncol., 5: 511-520, 2017.
  69. Patel, N.H., Schulman, A.A., Bloom, J.B., Uppaluri, N., Phillips, J.L., Konno, S., Choudhury, M. and Eshghi, M. Device-related adverse events during percutaneous nephrolithotomy: review of the manufacturer and user facility device experience database. J. Endourol., 31: 1007-1011, 2017.
  70. Fox, C., Yau, R., Choudhury, M., Phillips, J. and Konno, S. Anticancer effect of medicinal mushroom with prooxidant activity on human bladder cancer cells. J. Cancer Res. Treat., 6: 54-59, 2018.
  71. Zhang, M., Zheng, K, Choudhury, M., Phillips, J. and Konno, S.: Enhanced anticancer effect by combination of proteoglucan and vitamin K3 on bladder cancer cells. Cancer Transl. Med., 4: 117-122, 2018.
  72. Wagmaister, J., Yau, R., Choudhury, M., Eshghi, M. and Konno, S.: Amelioration of chronic kidney disease (CKD) with medicinal mushroom extract in rats. J. Urol. Res., 5: 1107 -1112, 2018.
  73. Yau, R., Wagmaister, J., Choudhury, M., Eshghi, M. and Konno, S.: Protective effect of mushroom extract against adenine-induced chronic kidney disease mediated through oxidative stress in a rat model. J. Oncol. Res. Ther., 6: 1-7, 2018.
  74. Bloom, J., Patel, N., Wagmaister, J., Choudhury, M., Eshghi, M. and Konno, S.: Prophylactic effect of ethyl pyruvate on ischemia/reperfusion injury mediated through oxidative stress. Int. Urol. Nephrol., 51: 85-92, 2019.
  75. Patel, N.H., Uppaluri, N., Iorga, M., Schulman, A., Bloom, J.B., Phillips, J., Fullerton, S., Konno, S., Choudhury, M. and Eshghi, M.: Device malfunctions and complications associated with benign prostatic hyperplasia surgery: Review of the manufacturer and user facility device experience database. J. Endourol., 33; 448- 454, 2019.
  76. Konno, S.: Possible impediment of b-amyloid-facilitated Alzheimer’s disease progression with amycenone (AMY) isolated from mushroom. Townsend Lett., Oct.: 27-31, 2019.
  77. Wagmaister, J., Zheng, K., Choudhury, M., Eshghi, M. and Konno, S.: Possible prophylactic effect of Poria mushroom extract on chemically-induced chronic kidney disease in vitro and in vivo. Int. J. Innov. Res. Med. Sci., 4: 600-606, 2019.
  78. Stern, M., Iskander, M., Zheng, K., Choudhury, M. and Konno, S.: Prooxidant activity of Poria mushroom extract on renal cell carcinoma: Potential therapeutic strategy. J. Urol. Ren Dis., 5: 1187-1192, 2020.
  79. Wagmaister, J., Gopal, N., Patel, N., Choudhury, M., Eshghi, M. and Konno, S.: Prevention of calcium oxalate crystal formation with medicinal mushroom extract with antioxidant activity in a rat model. J. Compl. Med. Res., 11; 351-357, 2020.
  80. Hillelsohn, J., Stern, M., Iskander, M., Choudhury, M. and Konno, S.: Chemosensitizing effect of maitake mushroom extract on carmustine cytotoxicity in human bladder cancer cells. Int. J. Res. Med. Sci., 8; 3154-3159, 2020.
  81. Yau, R., Bloom, J., Wagmaister, J., Eshghi, M., Choudhury, M. and Konno, S.: Prophylactic effect of ethyl pyruvate on renal ischemia/reperfusion injury in rats. Urol. Nephrol. Open Access J., 8: 102-107, 2020.
  82. Konno, S.: SX-fraction: Promise for novel treatment of type 2 diabetes. World J. Diabetes., 11; 572-583, 2020.

 

Abstract/Paper Presentations at Major Urological Meetings/Events: (1996 – Present)

 

American Urological Association (AUA) Meeting

  1. Attenuation of androgenic regulation by brefeldin A (BFA) in LNCaP cells. (1996) Konno, S., Chen, Y., Wu, J.M. and Mallouh, C. Abst. #787, The 91st AUA Annual Meeting (Orlando, FL).

  2. Effects of brefeldin A (BFA) on G1 cell cycle progression in prostate cancer PC-3 cells. (1996) Mordente, J.A., Konno, S., Tazaki, H., Wu, J.M. and Mallouh, C. Abst. #P19, The 65th Annual Meeting of New England Section of AUA (Lake George, NY) and Abst. #32, The 48th Annual Meeting of Northeastern Section of AUA (Buffalo, NY).

  3. The modulation of the retinoblastoma (pRB) protein by brefeldin A (BFA) during G1 cell cycle progression in prostate cancer PC-3 cells. (1997) Mordente, J.A., Konno, S., Chen, Y., Wu, J.M., Tazaki, H. and Mallouh, C. Abst. #30, The 92nd AUA Annual Meeting (New Orleans, LA). Awarded “Third” Prize in the 1997 AUA/Circon-ACMI Prize Essay Contest
  4. Molecular analysis of cathepsin D and its biological significance in human prostate cancer. (1997) Cherry, J.P., Konno, S., Mordente, J.A., Chapman, J.R., Tazaki, H. and Mallouh, C. Abst. #45, The 66th Annual Meeting of New England Section of AUA (Boston, MA) and Abst. #P20, The 49th Annual Meeting of Northeastern Section of AUA (Litchfield, AZ).

  5. Life sustaining function of glyoxalase I in human prostate cancer: Role of cell survival. (1999) Davidson, S.D., Milanesa, D.M., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Abst. #517, The 94th AUA Annual Meeting (Dallas, TX). Awarded “Second” Prize in the 1999 AUA/Circon-ACMI Prize Essay Contest.

  6. Effects of antioxidants on renal injury induced by reactive oxygen metabolites: Experimental prevention and therapeutic implications. (1999) Nowzari, F.B., Davidson, S.D., Eshghi, M., Tazaki, H., Mallouh, C. and Konno, S. Abst. #322, The 94th AUA Annual Meeting (Dallas, TX).

  7. Induction of cell death by vitamin combination in prostate cancer: A Ca2+- dependent death pathway. (2000) Won, J.H., Finkelstein, M.P., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Abst. #117, The 95th AUA Annual Meeting (Atlanta, GA). Awarded “First” Prize in the 2000 AUA/Circon-ACMI Prize Essay Contest.

  8. Mode of action of nephrotoxic agents in renal cell injuries: Oxidative stress and heat shock protein degradation. (2000) Tortorelis, D.G., Drinis, S., Finkelstein, M.P., Eshghi, M., Tazaki, H. and Konno, S. Abst. #18, The 52nd Annual Meeting of Northeastern Section of AUA (Pittsburgh, PA).

  9. Glyoxalase I as a potential factor involved in multidrug resistance of prostate adenocarcinoma. (2000) Drinis, S., Finkelstein, M.P., Choudhury, M.S., Tazaki, H. and Konno, S. Abst. #23, The 58th Annual Meeting of Mid-Atlantic Section of AUA (Rio Grande, Puerto Rico).

  10. Mode of cytotoxic action of nephrotoxic agents: Involvement of oxidative stress and glutathione-dependent enzyme. (2002) Tortorelis, D.G., Aynehchi, S., Dolin, D.J., Choudhury, M.S., Eshghi, M., Tazaki, H. and Konno, S. Abst. #392, The 2002 AUA Annual Meeting (Orlando, FL).

  11. George Nagamatsu: Urologist, engineer and pioneer. (2004) Johnson, G.B., Vitenson, J.H., Konno, S. and Choudhury, M.S. Abst. #1225, The 2004 AUA Annual Meeting (San Francisco, CA).

  12. Enhanced antiproliferative activity of interferon-2b combined with proanthocyanidin on bladder cancer cells. (2004) Johnson, G.B., Landau, L.M., Samadi, A.A., Tazaki, H., Choudhury, M.S. and Konno, S. Abst. #973, The 2004 AUA Annual Meeting (San Francisco, CA).

  13. Possible biochemical events critically involved in acute renal cell injury. (2009) Louie, B., Rajamahanty, S., Pyo, P., Won, J., Choudhury, M. and Konno, S. The 2009 AUA Annual Meeting (Chicago, IL).

  14. Synergistic potentiation of interferon with D-fraction on bladder cancer cells. (2009) Louie, B., Davalos, M., Pyo, P., Won, J., Choudhury, M. and Konno, S. The 2009 AUA Annual Meeting (Chicago, IL).

  15. Preventive effect of specific antioxidant on oxidative renal cell injury facilitating renal crystal formation: In vitro and in vivo studies. (2011) Fishman, A.I., Green, D., Lynch, A., Choudhury, M., Eshghi, M. and Konno, S. The 2011 AUA Annual Meeting (Washington D.C.).

  16. Comparison of anticancer effects of two combination trials in urological cancer cells: Chemotherapeutic drugs combined with D-fraction versus D-fraction with vitamin C. (2012) Alexander, B., Fishman, A., Eshghi, M., Choudhury, M. and Konno, S. The 2012 AUA Annual Meeting (Atlanta, GA).

  17. Alternative therapeutic approach using vitamin K3 and D-fraction for renal cell carcinoma targeting cell cycle and chromatin structure. (2013) Alexander, B., Degen, M., Fishman, A., Choudhury, M., Eshghi, M. and Konno, S. The 2013 AUA Annual Meeting (San Diego, CA).

  18. Comparison of protective effects of N-acetylcysteine and mannitol on renal ischemic/reperfusion injury. (2013) Degen, M., Fishman, A., Alexander, B., Choudhury, M., Eshghi, M. and Konno, S. The 2013 AUA Annual Meeting (San Diego, CA).

  19. Anticancer and chemosensitizing effects of 2-deoxyglucose targeting glycolysis in human bladder cancer cells. (2016) Valera, V., Prabharasuth, D., Bloom, J., Phillips, J., Choudhury, M. and Konno, S. The 2016 AUA Annual Meeting (San Diego, CA).

  20. Protective effect of ethyl pyruvate on oxidative renal cell injury: Implication in prevention of renal ischemia/reperfusion injury. (2017) Bloom, J., Ferretti, M., Chaimowitz, M., Choudhury, M., Eshghi, M. and Konno, S. The 2017 AUA Annual Meeting (Boston, MA).

F.C. Valentine Urology Residents’ Essay Meeting

  1. Cathepsin D-mediated hydrolysis of the androgen receptor and its implication in human prostate adenocarcinomas. (1997) Mordente, J.A., Chapman, J.R., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #101. Awarded “Second” Prize.
  2. Cell cycle-regulated growth inhibition and possible induction of apoptosis by brefeldin A (BFA) in human prostate cancer DU-145 cells. (1997) Chapman, J.R., Wu, J.M., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #99. Awarded “Honorable Mention”.
  3. The effects of ammonium chloride on prostatic cancer cells: Induction of hypertrophy. (1998) Won, J.H., Parekattil, S.J., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #76.Molecular analysis of cathepsin D and its clinical relevance in human prostate cancer. (1998) Cherry, J.P., Mordente, J.A., Chapman, J.R., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #94. Awarded “Third” Prize.
  4. Life sustaining function of glyoxalase I in human prostate cancer: Its role in cell survival. (1999) Davidson, S.D., Milanesa, D.M., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #L2.
  5. Apoptotic cell death in human prostate cancer by methylglyoxal: A natural apoptosis inducer. (1999) Milanesa, D.M., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #L19.
  6. Effects of antioxidants on renal injury induced by reactive oxygen metabolites: Experimental Prevention and therapeutic implications. (1999) Nowzari, F.B., Davidson, S.D., Mallouh, C., Tazaki, H., Eshghi, M. and Konno, S. Ppr. #C22.
  7. Significance of glycosylation of cellular PSA in relation to serum PSA levels. (1999) Samadi, A.A., Davidson, S.D., Mordente, J.A., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Ppr. #C23.
  8. Synergistic cytotoxic effect of vitamin C and K3 combination on prostate cancer cells: Mechanism and therapeutic implications. (1999) Won, J.H., Davidson, S.D., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #L12.
  9. Critical role of cathepsin D in prostatic cancer cell growth and its regulation by brefeldin A: Therapeutic implication. (1999) Cherry, J.P., Mordente, J.A., Chapman, J.R., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #C18. Awarded “Third” Prize.
  10. Possible role of glyoxalase I in multidrug resistance of prostate cancer. (2000) Finkelstein, M.P., Fullerton, S.A., Mallouh, C., Choudhury, M.S., Tazaki, H. and Konno, S. Ppr. #52. Awarded “Honorable Mention”.
  11. Heat shock protein 90 as a potential biochemical marker for acute renal injury. (2000) Tortorelis, D.G., Drinis, S., Eshghi, M., Choudhury, M.S., Tazaki, H. and Konno, S. Ppr. #53.
  12. Glyoxalase I phenotype as a potential genetic marker for prostate carcinogenesis. (2000) Samadi, A.A., Fullerton, S.A., Tortorelis, D.G., Johnson, G.B., Davidson, S.D., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #58.
  13. Mechanism of cell death induced by vitamin combination in prostate cancer: A possible Ca2+-dependent death pathway. (2000) Won, J.H., Finkelstein, M.P., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #59.
  14. Significance of glyoxalase I in glycolytic process in human prostate carcinoma. (2000) Davidson, S.D., Milanesa, D.M., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Ppr. #61.
  15. Differential protein kinase systems in growth regulation of prostatic cancer cells. (2001) Dolin, D., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S.
  16. Apoptotic cell death induced by b-glucan in androgen-independent prostatic cancer cells. (2001) Fullerton, S.A., Samadi, A.A., Tortorelis, D.G., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S.
  17. Antiproliferative activity of brefeldin A on androgen-responsive prostatic cancer cells: Its effects on cell cycle and androgen receptor. (2001) Drinis, S., Dolin, D., Choudhury, M.S., Tazaki, H. and Konno, S.
  18. Successful extracorporeal shockwave lithotripsy after failed ureteroscopy. (2001) Aynehchi, S., Samadi, A.A., Gallo, S.J., Konno, S., Tazaki, H. and Eshghi, M.
  19. Cytotoxic mechanism of nephrotoxic agents: Role of oxidative stress and glutathione-dependent enzyme. (2002) Aynehchi, S., Tortorelis, D.G., Dolin, D.J., Choudhury, M.S., Eshghi, M., Tazaki, H. and Konno, S. Awarded “Second” Prize.
  20. Antiproliferative mechanism of interferon-b in prostate cancer cells. (2002) Dolin, D.J., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S.
  21. Sensitized cytotoxic effect of carmustine with b-glucan on androgen-independent prostatic cancer cells. (2002) Finkelstein, M.P., Aynehchi, S., Samadi, A.A., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S. Awarded “Second” Prize.
  22. Holmium laser enucleation of the prostate (HoLEP) for prostates greater than 100 ml in volume. (2002) Hettiarachchi, J.A., Samadi, A.A., Konno, S. and Das, A.K.
  23. Psychosocial variations in diverse ethnic and racial populations and their influence on the incidence of prostate cancer. (2002) Moss, V.J., Konno, S. and Choudhury, M.S.
  24. Potentiated growth inhibitory effect of interferon combined with proanthocyanidin on bladder cancer cells. (2002) Schwartz, A.M., Aynehchi, S., Moss, V.J., Choudhury, M.S., Tazaki, H. and Konno, S.
  25. Synergistic antiproliferative activity of interferon-a2b and b-glucan combination on prostatic cancer cells. (2003) Aynehchi, S., Johnson, G.B., Landau, L.M., Tazaki, H., Choudhury, M.S. and Konno, S.
  26. Possible detoxifying and protective roles of glyoxalase I and heat shock proteins in renal cell injury. (2003) Landau, L.M., Aynehchi, S., Tazaki, H., Choudhury, M.S. and Konno, S.
  27. Incidence of second primary bladder cancer following contemporary high-dose pelvic radiation therapy for prostate cancer patients. (2004) Aynehchi, S., Tracy, K., Xu, W., Konno, S. and Choudhury, M.S.
  28. Possible significance of cathepsin D in the growth regulation of androgen- dependent prostate cancer. (2004) Tracy, K., Aynehchi, S., Tazaki, H., Choudhury,M.S. and Konno, S.
  29. Accuracy of three dimensional computed tomography in pre-operative evaluation of renal vasculature for laparoscopic living donor nephrectomies. (2005) Grewall, P., Simon, R.B., Konno, S., Choudhury, M.S. and Edye, M.
  30. Role of signal transduction system in regulation of prostate cancer cell growth. (2006) Louie, B., Tracy, K., Aynehchi, S., Tazaki, H., Choudhury, M.S. and Konno, S.
  31. Antiproliferative effect of interferon on bladder cancer cells is enhanced by natural beta-glucan. (2006) Davalos, M., Hoffman, M., Tazaki, H., Choudhury, M.S. and Konno, S.
  32. Antibiotic-induced growth inhibition in human prostate cancer cells. (2006) Simon, R.B., Grewall, P., Davalos, M., Choudhury, M.S. and Konno, S.
  33. Potential effects of various natural products on growth of bladder cancer cells. (2006) Tracy, K., Davalos, M., Hoffman, M., Choudhury, M.S. and Konno, S.
  34. Do extended core prostate biopsies increase cancer detection? (2006) Xu, W., Greewall, P., Konno, S. and Choudhury, M.S.
  35. Cell cycle regulation in bladder cancer cells by specific mushroom extract (PL- fraction). (2008) Louie, B., Pyo, P., Choudhury, M.S. and Konno, S.
  36. Synergistic antiproliferative effect of beta-glucan combined with vitamin C on renal cell carcinoma. (2008) Hoffman, M., Davalos, M., Louie, B., Choudhury,M.S. and Konno, S.
  37. Cell death induced by blocking of glycolysis in metastatic prostate cancer cells. (2008) Davalos, M., Hoffman, M., Choudhury, M.S. and Konno, S.
  38. Enhanced growth inhibition with cell cycle arrest by combination of interferon and beta-glucan in prostate cancer cells. (2009) Pyo, P., Louie, B., Rajamahanty, S., Choudhury, M. and Konno, S.
  39. Induction of apoptosis by beta-glucan potentiated with vitamin C in renal cell carcinoma. (2009) Rajamahanty, S., Louie, B., Pyo, P., Choudhury, M. and Konno, S.
  40. Possible cytoprotective roles of glyoxalase I and heat shock proteins in acute renal cell injury. (2009) Louie, B., Rajamahanty, S., Pyo, P., Choudhury, M. and Konno, S.
  41. Attenuation of androgenic regulation by brefeldin A (BFA) in androgen-responsive prostate cancer cells. (2010) Alexander, B., Fishman, A.I., Green, D., Choudhury,M. and Konno, S. Awarded “First” Prize.
  42. Preventative effect of antioxidants on oxidative renal cell injury and the role in renal crystal formation. (2011) Green, D., Fishman, A.I., Lynch, A., Choudhury, M., Eshghi, M. and Konno, S. Awarded “Second” Prize.
  43. Apoptosis induced by combination of D-fraction and vitamin C in renal cell carcinoma. (2011) Alexander, B., Fishman, A.I., Choudhury, M. and Konno, S. Awarded “Third” Prize.
  44. Enhanced antiproliferative effect of combination of proteoglucan and vitamin K3 in bladder cancer cells. (2012) Alexander, B., Fishman, A., Eshghi, M., Choudhury,M. and Konno, S. Awarded “Second” Prize.
  45. Exploration of anticancer mechanism of 2-deoxyglucose in cultured bladder cancer cells. (2013) Prabharasuth, D., Freilich, D., Choudhury, M., Phillips, J. and Konno, S.
  46. Therapeutic approach using combinations of chemotherapeutic drugs, D-fraction and vitamin C for urological cancer cells. (2013) Freilich, D., Moskowitz, E., Choudhury, M., Phillips, J. and Konno, S. Awarded “Second” Prize.
  47. Protection against renal ischemia/reperfusion injury with N-acetylcysteine versus mannitol: Is there a difference? (2014) Moskowitz, E., Degen, M., Choudhury, M., Eshghi, M. and Konno, S. Awarded “Third” Prize.
  48. Anticancer effects of three bioactive fractions isolated from mushroom on urothelial cell carcinoma. (2015) Bhalodi, A., Valera, V., Choudhury, M., Phillips, J. and Konno, S. Awarded “Third” Prize.
  49. Preclinical model of dual-specific, mTOR complex 1 (TORC1) and mTOR complex 2 (TORC2) inhibitors for bladder cancer treatment. (2015) Valera, V., Choudhury, M., Phillips, J. and Konno, S.
  50. Is targeting glycolysis a potential therapeutic modality for bladder cancer? – an alternative approach. (2016) Ferretti, M., Valera, V., Chaimowitz, M., Choudhury, M., Phillips, J. and Konno, S.
  51. Is ethyl pyruvate a more effective prophylactic agent for prevention of oxidative renal cell injury? (2017) Bloom, J., Chaimowitz, M., Choudhury, M., Eshghi, M. and Konno, S. Awarded “Second” Prize.
  52. Chemosensitization of carmustine with mushroom b-glucan on human bladder cancer cells. (2018) Hillelsohn, J., Chaimowitz, M., Choudhury, M., Phillips, J. and Konno, S.
  53. Oxidative stress-mediated anticancer effect of mushroom extract on bladder cancer cells. (2018) Fox, C., Yau, R., Chaimowitz, M., Choudhury, M., Phillips, J. and Konno, S. Awarder “Third” Prize.
  54. Prophylactic effect of ethyl pyruvate on renal ischemic/reperfusion injury in rats. (2018) Yau, R., Bloom, J., Choudhury, M, Eshghi, M. and Konno, S. Awarded “First” Prize.
  55. Prevention of calcium oxalate stone formation with Poria mushroom extract with antioxidant activity. (2019) Patel, N., Wagmaister, J., Gopal, N., Choudhury, M., Eshghi, M. and Konno, S. Awarded “First” Prize.

Annual Endourology Fellow Essay Contest

 

  • Oxidative renal cell injury induced by calcium oxalate crystal and renoprotection with antioxidants: a possible role of oxidative stress in nephrolithiasis (2010). Davalos, M., Choudhury, M., Eshghi, M. and Konno, S. Awarded “First” Place in the 2010 Annual Endourology Fellow Essay
  • Alternative therapeutic approach to renal-cell carcinoma: induction of apoptosis with combination of vitamin K3 and D-fraction (2013). Degen, M., Alexander, B.,Choudhury, M., Eshghi, M. and Konno, S. Awarded “Third” Place in the 2013 Annual Endourology Fellow Essay
  • Antioxidant and renoprotective effects of mushroom extract against oxidative stress: implication in prevention of nephrolithiasis (2016). Schulman, A., Chaimowitz, M., Choudhury, M., Eshghi, M. and Konno, S. Awarded “First” Place in the 2016 Annual Endourology Fellow Essay

Other Meetings/Conferences

  1. Inhibitory effects of brefeldin A (BFA) on the growth of human prostate cancer DU-145 cells. (1996) Chapman, J.R., Konno, S., Wu, J.M., Tazaki, H. and Mallouh, C. Abst. #45, The 44th Annual James C. Kimbrough Urological Seminar (Scottsdale, AZ). Awarded “Second” Place.
  2. The effects of brefeldin A (BFA) on G1 cell cycle progression involving the modulation of the retinoblastoma protein (pRB) in prostate cancer PC-3 cells. (1997) Mordente, J.A., Konno, S., Wu, J.M., Mallouh, C. and Tazaki, H. Abst. #25, The 6th Annual Meeting of the Urological Cell Analysis Research Society (Tokushima, Japan).
  3. Hydrolysis of androgen receptor by cathepsin D in human prostatic carcinoma LNCaP cells. (1997) Konno, S., Mordente, J.A., Wu, J.M., Mallouh, C. and Tazaki, H. Abst. #22, The 6th Annual Meeting of the Urological Cell Analysis Research Society (Tokushima, Japan).
  4. Apoptotic cell death of prostatic cancer PC-3 cells by methylglyoxal. (1998) Konno, S., Milanesa, D.M., Mallouh, C. and Tazaki, H. Abst. #S-8, The 16th Japan Human Cell Society Annual Meeting (Morioka, Japan).
  5. Growth inhibition and cell death in prostatic cancer DU-145 cells: Induction of apoptosis via possible p53-independent pathway by brefeldin A. (1998) Konno, S., Chapman, J.R., Mallouh, C. and Tazaki, H. Abst. #A-13, The 16th Japan Human Cell Society Annual Meeting (Morioka, Japan).
  6. Induction of prostatic hypertrophy by ammonium chloride and its implication in benign prostatic hyperplasia (BPH). (1998) Won, J.H., Parekattil, S.J., Luddy, J.S., Choudhury, M.S., Eshghi, M., Tazaki, H., Mallouh, C. and Konno, S. Abst. #BS6- 11, The 16th World Congress on Endourology and SWL (New York, NY).
  7. Cytotoxic effect of vitamin C and K3 combination on human prostatic cancer DU- 145 cells. (1999) Won, J.H., Davidson, S.D., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. Abst. #257 (P15), The 14th European Association of Urology (EAU) Congress (Stockholm, Sweden).
  8. Role of glyoxalase I in survival of human prostate cancer and its clinical implication. (1999) Davidson, S.D., Milanesa, D.M., Choudhury, M.S., Tazaki, H., Mallouh, C. and Konno, S. Abst. #297 (P17), The 14th EAU Congress (Stockholm, Sweden).
  9. Possible mechanism of drug-induced acute renal injury and its prevention by antioxidants. (1999) Nowzari, F.B., Davidson, S.D., Eshghi, M., Tazaki, H., Mallouh, C. and Konno, S. Abst. #1007, The 15th International Congress of Nephrology (Buenos Aires, Argentina).
  10. Growth inhibition of prostatic cancer cells via blocking of cathepsin D processing by brefeldin A: Alternative approach for prostate cancer treatment. (1999) Konno, S., Cherry, J.P., Mordente, J.A., Chapman, J.R., Choudhury, M.S., Mallouh, C. and Tazaki, H. Abst. #64, The 2nd International Consultation on Prostate Cancer (Paris, France).
  11. Apoptosis in prostatic cancer cells with Maitake mushroom extracts: Potential alternative therapy. (1999) Konno, S., Fullerton, S.A., Samadi, A.A., Tortorelis, D.G., Mallouh, C. and Tazaki, H. Abst. #13, The 7th Anti-Aging Conference (Las Vegas, NV).
  12. Induction of apoptosis in prostatic cancer cells by beta-glucan (Maitake mushroom extract): A potential therapeutic modality. (2000) Konno, S., Fullerton, S.A., Samadi, A.A., Tortorelis, D.G., Mallouh, C. and Tazaki, H. Abst. #163, The 2nd World Congress on The Aging Male (Geneva, Switzerland).
  13. Possible mechanism of acute renal cell injuries induced by nephrotoxic agents. (2000) Konno, S., Tortorelis, D.G., Drinis, S., Samadi, A.A., Eshghi, M., Choudhury, M.S. and Tazaki, H. Abst. #100, The 25th Congress of The Societe Internationale d’Urologie (SIU) (Singapore).
  14. Apoptosis induced by b-glucan (Maitake D-Fraction) in prostatic cancer cells: A potential therapeutic modality. (2000) Konno, S. and Tazaki, H. The 11th Food Design Exposition (Tokyo, Japan).
  15. Chemosensitization of carmustine with b-glucan (Maitake mushroom polysaccharide) in androgen-independent prostatic cancer cells: Involvement of glyoxalase I. (2000) Fullerton, S.A., Finkelstein, M.P., Samadi, A.A., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S. The 8th International Anti-Aging Conference (Las Vegas, NV).
  16. Enhanced cytotoxic effect of carmustine with b-glucan in prostatic cancer PC-3 cells: Role of glyoxalase I. (2001) Finkelstein, M.P., Fullerton, S.A., Samadi, A.A., Drinis, S., Choudhury, M.S., Tazaki, H. and Konno, S. The 11th International Prostate Cancer Update Conference (Vail, CO).
  17. Induction of apoptosis and chemosensitization by b-glucan (Maitake mushroom polysaccharide) in androgen-independent prostatic cancer cells: Alternative therapeutic modality for hormone-refractory prostate cancer. (2001) Konno, S., Fullerton, S.A., Finkelstein, M.P., Samadi, A.S., Drinis, S., Tortorelis, D.G., Choudhury, M.S. and Tazaki, H. The 1st Asian Therapies for Cancer Conference (New York, NY).
  18. Holmium laser enucleation of the prostate with transurethral soft tissue morcellation for prostates greater than 100 ml in volume. (2001) Hettiarachchi, J.A., Konno, S. and Das, A.K. The 21st Annual American Society for Laser Medicine and Surgery Meeting (New Orleans, LA). Awarded “Best” paper.
  19. Glyoxalase I phenotype as a potential risk factor for prostate carcinoma. (2001) Fullerton, S.A., Samadi, A.A., Tortorelis, D.G., Johnson, G.B., Davidson, S.D., Choudhury, M.S., Mallouh, C., Tazaki, H. and Konno, S. The 2001 Chief Residents in Urology Meeting for the Society of University Urology Residents (SUUR) (Newport Beach, CA).
  20. Laparoscopic repair of colovesical fistula. (2001) Samadi, A.A., Teixeira, J.A., Eshghi, M., Konno, S. and Tazaki, H. Abst. #C1-P12, The 19th World Congress on Endourology and SWL (Bangkok, Thailand).
  21. Urologic applications of holmium-YAG laser. (2001) Samadi, A.A., Das, A., Eshghi, M., Konno, S. and Tazaki, H. Abst. #D3-P11, The 19th World Congress on Endourology and SWL (Bangkok, Thailand).
  22. Management of impacted mid-ureteral stones using digital flexiblescope evaluating the life durability. (2001) Samadi, A.A., Fullerton, S.A., Konno, S., Eshghi, M. and Tazaki, H. Abst. #V3-P6, The 19th World Congress on Endourology and SWL (Bangkok, Thailand).
  23. Treatment of erectile dysfunction by combination intracavernous injection therapy: Is ‘cure’ possible? (2002) Tazaki, I., Tortorelis, D.G., Aynehchi, S., Konno, S. and Tazaki, H. Abst. #133, The 3rd World Congress on The Aging Male (Berlin, Germany).
  24. Enhanced cytotoxic activity of carmustine with maitake beta-glucan on prostate cancer cells. (2002) Finkelstein, M.P., Tortorelis, D.G., Samadi, A.A., Aynehchi, S., Choudhury, M.S., Tazaki, H. and Konno, S. Abst. #135, The 3rd World Congress on The Aging Male (Berlin, Germany).
  25. Inhibitory mechanism of brefeldin A on androgen-mediated prostatic cancer cell growth. (2002) Drinis, S., Dolin, D.J., Schwartz, A.M., Choudhury, M.S., Tazaki, H. and Konno, S. Abst. #124, The 17th EAU Congress (Birmingham, UK).
  26. Sensitized cytotoxic effect of carmustine with b-glucan on androgen-independent prostatic cancer cells: Role of glyoxalase I. (2002) Finkelstein, M.P., Samadi, A.A., Aynehchi, S., Tortorelis, D.G., Choudhury, M.S., Tazaki, H. and Konno, S. Abst. #117, The 17th EAU Congress (Birmingham, UK).
  27. Cytotoxic mechanism of nephrotoxic agents: Role of oxidative stress and heat shock protein. (2002) Moss, V.J., Aynehchi, S., Choudhury, M.S., Eshghi, M., Tazaki, H. and Konno, S. The 2002 National Medical Association (NMA) Meeting (Hawaii).
  28. Minimized invasiveness and maximized effects in intra-cavernous injection therapy for patients with erectile dysfunction. (2002) Tazaki, I., Tazaki, G., Kawashima, S., Tortorelis, D.G., Konno, S., Choudhury, M.S. and Tazaki, H. The 2002 Society for Medical Innovation and Technology (SMIT) Conference (Oslo, Norway).
  29. Thermal therapies of the benign and malignant prostate diseases: Comparative analysis of different energy sources and mechanism in long-term efficacy. Tazaki, H., Nakamura, K., Konno, S., Eshghi, M. and Choudhury, M.S. (2002) The 2002 SMIT Conference (Oslo, Norway).
  30. Intra-cavernous injection of papaverine and prostaglandin E1: Follow-up study of age matched low dose therapy in 420 patients and cure rate. (2002) Tazaki, I., Tazaki, G., Tortorelis, D.G., Konno, S. and Tazaki, H. The 26th Congress of SIU (Stockholm, Sweden).
  31. Spontaneous renal rupture in hemodialysis patients. (2002) Tazaki, H., Aynehchi, S., Samadi, A., Konno, S., Choudhury, M.S. and Eshghi, M. The 26th Congress of SIU (Stockholm, Sweden).
  32. Holmium laser use in critically ill patients. (2002) Tazaki, H., Aynehchi, S., Samadi, A., Konno, S., Choudhury, M.S. and Eshghi, M. The 26th Congress of SIU (Stockholm, Sweden).
  33. Synergistic antiproliferative effects of interferon-a2b and b-glucan combination on prostate cancer cells. (2002) Johnson, G.B., Moss, V.J., Dolin, D.J., Tazaki, H., Choudhury, M.S. and Konno, S. Abst. #09-58, The 78th Annual Meeting of Western Section AUA (Kauai, HI).
  34. Synergistic antiproliferative activity of interferon-a2b and maitake beta-glucan combination on prostate cancer cells. (2002) Konno, S. The 1st International Conference of Cancer Integrative Medicine (Chicago, IL).
  35. Beta-glucan as an immune therapy to prevent PSA recurrence in aged prostate cancer patients. (2004) Tazaki, H., Konno, S. and Choudhury, M.S. Abst. #40, The 4th World Congress on The Aging Male (Prague, Czech Republic).
  36. Review of intra-cavernous cocktail injection therapy (ICCIT) for sildenafil refractory organic and non-organic erectile failure. (2004) Tazaki, H., Tazaki, I., Tazaki, G., Tracy, K., Konno, S. and Choudhury, M.S. The 27th Congress of SIU (Honolulu, HI).
  37. Combination of interferon-a2b and b-glucan has synergistic antiproliferative effect on prostate cancer cells. (2004) Tracy, K., Landau, L.M., Johnson, G.B., Samadi, A.A., Tazaki, H., Choudhury, M.S. and Konno, S. The 27th Congress of SIU (Honolulu, HI).
  38. Beta-glucan, an immune enhancer, prevents biochemical recurrence in patients with localized prostate cancer. (2004) Tazaki, H., Fullerton, S.A., Tracy, K., Choudhury, M.S., Konno, S. and Nakamura, S. The 27th Congress of SIU (Honolulu, HI).
  39. Incidence of second primary bladder cancer following high-dose pelvic radiation therapy for prostate cancer patients. (2004) Tracy, K., Xu, W., Tazaki, H., Konno,and Choudhury, M.S. (2004) The 27th Congress of SIU (Honolulu, HI).
  40. The 29th Congress of SIU (Paris, France). A Comparison of systematic prostate biopsy strategies and their ability to detect clinically significant cancers: Are extended core biopsies necessary? (2005) Simon, R.B., Tracy, K., Belletete, B., Konno, S., Ahmed, T. and Choudhury, M.S. The 2005 American Association for Cancer Research (AACR) Annual Meeting (Anaheim, CA).
  41. Regulation of cell cycle and androgen receptor by brefeldin A in androgen- responsive prostate cancer cells. (2005) Simon, R.B., Aynehchi, S., Tazaki, H., Choudhury, M.S., Oyama, M. and Konno, S. The 2005 AACR Annual Meeting (Anaheim, CA).
  42. Accuracy of three dimensional computed tomography in pre-operative evaluation of renal vasculature for laparoscopic living donor nephrectomies. (2005) Grewall, P., Simon, R.B., Amukele, S.A., Konno, S., Choudhury, M.S. and Edye, M. The 23rd World Congress on Endourology and SWL (Amsterdam, Netherlands).
  43. Effects of antibiotic brefeldin A on growth of androgen-responsive prostate cancer cells and its potential regulator  a mechanisms. (2005) Simon, R.B., Amukele, S.A., Grewall, P., Tazaki, H., Choudhury, M.S. and Konno, S. The 23rd World Congress on Endourology and SWL (Amsterdam, Netherlands).
  44. Possible cytoprotective roles of Glyoxalase I and heat shock proteins in acute renal cell injury. (2007) Pyo, P., Hoffman, M., Tazaki, H., Choudhury, M.S. and Konno,
  45. Potent effects of two distinct mushroom extracts on growth of bladder cancer cells. (2007) Pyo, P., Hoffman, M., Grewall, P., Tazaki, H., Choudhury, M.S. and Konno, The 29th Congress of SIU (Paris, France). The 2013 Congress of SIU (The Societe Internationale d’Urologie) (Vancouver, Canada)
  46. . Induction of apoptosis in renal cell carcinoma by combination of maitake mushroom extract (PDF) and vitamin C. (2008) Louie, B., Pyo, P., Seiter, K., Tazaki, H., Choudhury, M.S. and Konno, S. The 2008 AACR Annual Meeting (San Diego, CA).
  47. Potent growth inhibitory activity of mushroom extract (PL-fraction) on human urological cancer cells. (2008) Louie, B., Pyo, P., Ahmed, T., Tazaki, H., Choudhury, M.S. and Konno, S. The 2008 AACR Annual Meeting (San Diego, CA).
  48. Enhanced antiproliferative activity of interferon with maitake mushroom extract (PDF) on prostate cancer cells. (2008) Pyo, P., Louie, B., Chiao, J.W., Tazaki, H., Choudhury, M.S. and Konno, S. The 2008 AACR Annual Meeting (San Diego, CA).
  49. Effects of maitake D-fraction on prostate, bladder, kidney, and breast cancers: Alternative and adjuvant therapeutic approach. (2008) Konno, S. The 36th Cancer Convention (Universal City, CA).
  50. Prophylactic effect of specific antioxidants on the formation of renal crystals in a rat model. (2010) Lankford, D., Fishman, A.I., Lynch, A., Choudhury, M., Eshghi,M. and Konno, S. The 28th World Congress on Endourology and SWL (Chicago, IL).
  51. Biochemical factors involved in cytoprotection against nephrotoxin-induced acute renal cell injury. (2010) Lankford, D., Fishman, A.I., Choudhury, M., Eshghi, M. and Konno, S. The 28th World Congress on Endourology and SWL (Chicago, IL).
  52. Tyrosine kinase inhibitors in bladder cancer as a potential role for targeted therapy. (2010) Lankford, D., Lynch, A., Zade, J., Choudhury, M., Konno, S. and Phillips, J. The 2010 Annual Meeting of American Society of Clinical Oncology (ASCO) (Hollywood, FL).
  53. The antiproliferative effect of interferon with proanthocyanidin in human bladder cancer cells. (2010) Fishman, A.I., Alexander, B., Green, D., Lankford, D., Choudhury, M. and Konno, S. The 2010 Annual Meeting of ASCO (Hollywood, FL).
  54. Synergistic antiproliferative effect of combination of mushroom beta-glucan and vitamin C on renal cell carcinoma: Induction of apoptosis. (2010) Fishman, A., Alexander, B., Green, D., Choudhury, M., Phillips, J. and Konno, S. The 2010 Annual Meeting of the Society of Urologic Oncology (SUO) (Bethesda, MD).
  55. Enhanced antiproliferative effect of combination of D-fraction and vitamin K3 in bladder cancer cells. (2012) Konno, S., Alexander, B., Fishman, A., Eshghi, M. and Choudhury, M. The 2012 Congress of SIU (The Societe Internationale d’Urologie) (Fukuoka, Japan).
  56. Exploration of anticancer mechanism of 2-deoxyglucose in cultured bladder cancer cells. (2013) Prabharasuth, D., Freilich, D., Phillips, J., Choudhury, M. and Konno,
  57. Preclinical model of dual-specific, mTOR complex 1 (TORC1) and mTOR complex 2 (TORC2) inhibitors for bladder cancer treatment. (2014) Valera, V., Choudhury, M., Phillips, J. and Konno, S. The 15th Annual Meeting of the Society of Urologic Oncology (SUO) (Bethesda, MD). Awarded “First” Prize.
  58. Standardized reporting of device-related adverse events during percutaneous nephrolithotomy: review of the manufacturer and user facility device experience (MAUDE) database. (2017) Patel, N.H., Schulman, A.A., Bloom, J.B., Uppaluri, N., Phillips, J.L., Konno, S., Choudhury, M. and Eshghi, M. The 35th World Congress of Endourology (Vancouver, Canada).

 

 

Grants/Fellowships:

 

  • Yamanouchi Research Grant from The New York Section of The American Urological Association to Dr. Janaka Hettiarachchi (PGY-4 resident) under supervision of Dr. Sensuke Konno – January,
  • Ferdinand C. Valentine Fellowship from The New York Academy of Medicine to Dr. Albert A. Samadi (chief resident) under supervision of Dr. Sensuke Konno – February,
  • I. Fund Grant from The Dr. I Fund Foundation to Drs. Sensuke Konno (P.I.) and Muhammad S. Choudhury – March, 2001.
  • Research Grant from Maitake Products, Inc. to Drs. Sensuke Konno (P.I.) and Muhammad S. Choudhury – November,
  • Research Grant from Maitake Products, Inc. to Drs. Sensuke Konno (P.I.) and Muhammad S. Choudhury – July,
  • Research Grant from Maitake Products, Inc. to Dr. Sensuke Konno (P.I.) – November,
  • Research Grant from American Holistic Veterinary Medical Association

(AHVMA) to Dr. Sensuke Konno (P.I.) – April, 2008.

  • Ferdinand Valentine Fellowship from The New York Academy of Medicine
  • Research Grant from Mushroom Wisdom, Inc. to Dr. Sensuke Konno (P.I.) – August,
  • Research Grant for the Empire Clinical Research Investigator Program (ECRIP) from the New York State Department of Health to Sensuke Konno sponsoring Dr. Michael Degen (as the Researcher) – July, 2011.
  • Research Grant from the “Seize the Ribbon” to Drs. John Phillips and Sensuke Konno – May, 2012 (to Present).
  • Research Grant from Mushroom Wisdom, Inc. to Dr. Sensuke Konno (P.I.) – February,
  • Research Grant from Saraya Co., Ltd. To Dr. Sensuke Konno (P.I.) – July, 2019.
  • Research Grant from Mushroom Wisdom, Inc. to Dr. Sensuke Konno (P.I.) – December,

to Dr. Mauricio Davalos under supervision of Dr. Sensuke Konno – July, 2008.

 

 

Achievements 

Three Prizes” won at the AUA Urology Resident Essay Contest: 

  • Third Prize:       John A. Mordente. “The modulation of the retinoblastoma (pRB) protein by brefeldin A (BFA) during G1 cell cycle progression in prostate cancer PC-3 cells” (1977)
  • Second Prize:     Scott D. Davidson. “Life sustaining function of glyoxalase I in human prostate cancer: Role of cell survival” (1999)
  • First Prize:        John H. Won. “Induction of cell death by vitamin combination in prostate cancer: A Ca-dependent death pathway” (2000) 

Seventeen Awards” won at the Valentine Urology Resident Essay Contest, including Three-Award Sweep (in the Research Category) in 2011: 

  • First Place:        Andrew I. Fishman. “Prevention of renal ischemia-reperfusion injury by a novel renoprotective cocktail in a rat model”
  • Second Place:     David A. Green. “Preventative effect of antioxidants on oxidative renal cell injury and the role in renal crystal formation”
  • Third Place:       Bobby Alexander. “Apoptosis induced by combination of D-fraction and vitamin C in renal cell carcinoma” 

“Sixty-nine Presentations”

  • Delivered at the National and International Meetings and Conferences (List available upon request).