Department of Medicine
New York Medical College
Valhalla, NY 10562
Michael S Goligorsky, M.D., Ph.D., holds the Alvin I. Goodman Chair in Nephrology, and is Professor of Medicine, Pharmacology and Physiology, Academic Chief of Renal Division, and Director of Renal Research Institute at the New York Medical College. After completing residency and fellowship, Michael joined the faculty of the State University of New York at Stony Brook (1988). He became a Professor of Medicine and Physiology in 1997 and named an Honorary Professor at the University College London (1998). In 2002 he was recruited by the New York Medical College to inaugurate Renal Research Institute. In 1991, Michael was elected to the American Society of Clinical Investigations; in 2002 elected to the American Association of Physicians. MSG serves as an Associate Editor for Am J Pathology, Am J Physiology: Cell, and a Topic Editor for Nephrology, Dialysis and Transplantation. His research interests include: the mechanisms of endothelial dysfunction as a harbinger of atherosclerotic, diabetic, and hypertensive vascular damage; stress-induced premature senescence (SIPS) of endothelial cells and the role of lysosomal dysfunction in this process; mechanisms of functional incompetence of endothelial progenitor cells (EPC) in chronic kidney disease; mechanisms of Alarm Signaling by an ischemic organ; and proteomic analysis of the urine in kidney disease.
Dr. Goligorsky heads the New York Medical College/Westchester Artificial Kidney Foundation Renal Institute (The Renal Institute), research teams are working to characterize the mechanisms of endothelial dysfunction as an early warning system of atherosclerotic, diabetic, and hypertensive vascular damage. Endothelial nitric oxide synthase represents the main parameter affected early during development of endothelial dysfunction, providing an opportunity to diagnose these conditions at a stage when symptoms are still absent.
Dr. Goligorsky studies integrins in acute renal failure, seeking the molecular pathology responsible for dislodgement of epithelial cells and the resultant tubular obstruction and renal dysfunction. Another study focuses on vascular permeability in diabetic nephropathy, and a third project explores the biology of nitric oxide (NO) in renal injury.
Graduate Degree: M.D., Ph.D.
Graduate Degree Institution: Kiev Medical Institute, Ukraine
Regenerative Nephrology. Edited by Michael S. Goligorsky