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Credits: 2
Immunopharmacology is a rapidly developing area of investigation that continues to evolve as our understanding of human disease reveals roles for the immune system in conditions such as rheumatoid arthritis, asthma, allergies, and autoimmune diseases as well as in, hypertension, atherosclerosis, ischemic-reperfusion injury, heart failure, and neurodegenerative disorders. This course will provide state-of-the-art information regarding mechanisms that underlie the cellular and molecular basis of immune system responses to a variety of conditions including chronic inflammatory diseases, cancer, COVID-19, autoimmunity and other selected diseases. Lectures will provide a description of the cell types, molecules, and effector mechanisms involved in innate and adaptive immune responses and will emphasize how uncovering immune system responses to disease can be leveraged to develop novel therapies. A goal of the course is for students to appreciate current trends in the field of Immunopharmacology including the development of novel antibody therapeutics, gene-based strategies, mRNA vaccines and therapeutics, as well as traditional pharmacological approaches for treating a variety of diseases.
Prerequisites:
Lectures: 2 hrs./wk. Letter-graded.