Assistant Professor of Cell Biology and AnatomyEmail: jdimarti@nymc.edu
Department of Cell Biology and Anatomy
Office Room 247, Lab Room 122
Basic Sciences Building
New York Medical College
Valhalla, NY 10595
(914) 594 4049
Education
Dr. Di Martino is from the Southwest region of France. She moved to Bordeaux, France to receive her college education. She earned a Bachelor’s degree in Cell Biology, a Master’s of Science in Genetics and a PhD in Cell Biology from the University of Bordeaux, France. She moved to New York City in 2016, shortly after graduating to complete a postdoctoral training at the Icahn school of Medicine at Mount Sinai Hospital, New York focusing on the role of the extracellular matrix in cancer dormancy.
Professional Interests
In 2020, Dr. Di Martino was awarded an Early Career Investigator Award from the METAvivor foundation supporting breast cancer research to investigate the effect of ACE inhibitors on dormant cancer cells. Most recently she was awarded the 2022 Rupert Timpl award from the International Society for Matrix Biology in recognition of her postdoctoral work recently published in Nature Cancer. Dr. Di Martino has published over 20 publications in respected peer-reviewed journals such as Journal of Cell Biology, Cancer Discovery, Nature, Nature Cancer, and Cell. Dr. Di Martino has trained numerous students in the last decade providing strong support and mentoring and is committed to train and mentor NYMC students from all levels. Joining New York Medical College as an Assistant Professor, her research will focus on Dormancy Escape and Cancer Metastasis using a combination of in vivo models and imaging technics.
Publications
Di Martino J, Nobre AR, Mondal C, Taha I, Farias E, Fertig E, Naba A, Aguirre-Ghiso J and Bravo-Cordero JJ A Collagen III-rich ECM niche regulates tumor dormancy. Nature Cancer 2022 PMID: 35121989
Di Martino J, Akhter M and Bravo-Cordero JJ Remodeling the ECM: implications for metastasis and tumor dormancy Cancers 2021 PMID: 34638400
Di Martino J, Mondal C, Bravo-Cordero JJ Textures of the tumour microenvironment Essays Biochem.2019 PMID: 31654075
Zhang M, Di Martino J, Bowman R, Campbell N, Baksh S, Simon-Vermot T, Kim I, Haldeman P, Mondal C, Yong-Gonzalez V, Abu-Akeel M, Merghoub T, Jones D, Zhu X, Arora A, Ariyan C, Birsoy K, Wolchok J, PanageasK, Hollmann T, Bravo-Cordero JJ, and White RM Adipocyte-derived lipids mediate melanoma progression via FATP proteins Cancer Discovery 2018 PMID: 29903879
Di Martino J*, Henriet E*, Zakaria Ezzoukhry Z, Mondal C, Bravo-Cordero JJ, Moreau V and Saltel F 2D and 3D matrices to study linear invadosome formation and activity JoVE 2017 PMID: 28605388
Di Martino J*, Henriet E*, Ezzoukhry Z*, Goetz JG, Moreau V, Saltel F The microenvironment controls invadosome plasticity Journal of Cell Science 2016 PMID: 27029343
Juin A*, Di Martino J*, Leitinger B, Paysan L, Bomo J, Baffet G, Rosenbaum J, Moreau V and Saltel F Discoidin domain receptor 1 controls linear invadosome formation, J Cell Biol 2014 PMID: 25422375
Presentations
2022
Invited speaker The key role of type III collagen in cancer dormancy Monthly Metastasis Working Group, Weill Cornell Medicine, Meyer Cancer Center & Englander Institute for Precision Medicine, NY
Invited speaker Cancer dormancy: an ECM perspective Bordeaux Institute of Oncology seminar series 2022, Bordeaux France (online)
Invited speaker Cancer dormancy: an ECM perspective Benchstorming seminars, VHIO, Spain (online)
Selected speaker A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy through a DDR1 STAT1 pathway EACR The structural microenvironment: Breaking down the walls of cancer 2022 (online)
Selected speaker A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy through a DDR1 STAT1 pathway EACR Seed and Soil: In Vivo Models of Metastasis 2022 (online)
2021
Selected speaker A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy Mechanical Forces and the 3D Sculpting of Cell-matrix Interactions and Tissues subgroup CELL BIO virtual 2021, online (selected from abstract)
Selected speaker The use of the Chicken Chorioallantoic Membrane model to study ECM Fibroblasts & ECM Remodeling session (Selected from abstract) ASMB The matrix in focus 2021, St Louis, Missouri, USA
Selected speaker A tumor cell self-made collagen III enriched ECM niche sustains cancer dormancy through a STAT1- DDR1 pathway MRD, Persister Cells and Dormancy Symposium (selected from abstract) EACR 2021 Innovative Cancer Science (Online)
2020
Selected speaker Collagen III activates a DDR1-STAT1 signaling pathway in tumor cells leading to the assembly of a pro-dormant ECM niche Seed and Soil meeting, 3-minute Poster Spotlight presentation (Selected for best abstract ranking 1/125) Berlin, Germany
2019
Selected speaker Collagen III activates a DDR1-STAT1 signaling pathway in tumor cells leading to the assembly of a pro-dormant ECM niche Seed and Soil meeting, 3-minute Poster Spotlight presentation (Selected for best abstract ranking 1/125) Berlin, Germany